Ana Kuya is the housekeeper at Duke Keramsov's estate at Keramzin. She is very strict and does not like disobedience. After Mal and Alina leave the orphanage, they tend to reminisce about the orphanage, and Ana Kuya is a big part of their memories there.
Ana Kuya is described as birdlike, with bony elbows.
She taught the Duke's orphans manners, and bade them pray for the Duke's generosity.
Throughout the series, Alina recalls things Ana Kuya said to her and Mal.
When Alina returns to Keramzin, she finds that Ana Kuya and Botkin Yul-Erdene have been killed.